What is the recommended air-drying method for newborn screening specimens?

The recommended air-drying method for newborn screening specimens is to air-dry flat and elevated. This method ensures that the specimens do not come into contact with any surfaces that could contaminate or affect the quality of the sample. When drying flat, the blood spots can dry uniformly, minimizing the risk of pooling or uneven drying that could compromise the integrity of the specimen. Elevating them allows for better airflow around the samples, further promoting proper drying while preventing dust or other contaminants from settling on the specimen. This approach is essential for maintaining the accuracy and reliability of screening tests, which are critical for early detection of potential health issues in newborns.

In contrast, air-drying upright might not provide adequate exposure to airflow on all sides of the sample and could lead to uneven drying. Air-drying in a closed container does not allow for adequate air circulation and could trap moisture, which is detrimental to the specimen. Air-drying with heat can damage the cells in the blood spots or alter their composition, leading to inaccurate test results.